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This website is intended for healthcare professionals and contains information about Mead Johnson Nutrition special infant formulas.

Important Notice: Breast feeding provides the best nutrition for babies. Mead Johnson special formulas are intended for bottle-fed infants and are Food for Special Medical Purposes (FSMPs) and must be used under medical supervision.

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Pregestimil LIPIL

The first choice for cow's milk allergy with fat malabsorption

Pregestimil LIPIL is an extensively hydrolysed hypoallergenic formula with 55% of fat as MCT oil, specially designed for babies with cow’s milk allergy (CMA) and fat malabsorption or maldigestion. Pregestimil LIPIL is nutritionally complete and suitable for babies from birth.

Hypoallergenic formula with MCT oil

  • The same extensively hydrolysed protein as Nutramigen LIPIL, with the lowest allergenic potential1
  • With medium chain triglycerides (MCT) – an easily digested source of energy2
    • Easily absorbed by infants with fat malabsorption2
    • Provides an abundant source of rapidly available energy2
  • Suitable for treatment of food allergy with malabsorptive enteropathy, as recommended by ESPGHAN3
  • Enriched with LIPIL – clinically proven to support brain and eye development4-6 Learn more

Degree of hydrolysis7


Clinically proven for infants with:

  • CMA or severe food enteropathy8
  • Fat malabsorption9-13
  • Pancreatic insufficiency9
  • Bile acid deficiency9,14


Show references
  1. Rosendal A, Barkholt V. Detection of potentially allergenic material in 12 hydrolyzed milk formulas. J Dairy Sci 2000;83:2200-10
  2. Bach AC, Babayan VK. Medium-chain triglycerides: an update. Am J Clin Nutr 1982;36:950-62.
  3. Host A, Koletzko B, Dreborg S et al. Dietary products used in infants for treatment and prevention of food allergy. Joint Statement of the European Society for Paediatric Allergology and Clinical Immunology (ESPACI) Committee on Hypoallergenic Formulas and the European Society for Paediatric Gastroenterology, Hepatology and Nutrition (ESPGHAN) Committee on Nutrition. Arch Dis Child 1999;81:80-4.
  4. Birch EE, Carlson SE, Hoffman DR et al. The DIAMOND (DHA Intake And Measurement Of Neural Development) Study: a double-masked, randomized controlled clinical trial of the maturation of infant visual acuity as a function of the dietary level of docosahexaenoic acid. Am J Clin Nutr 2010;91:848-59.
  5. Drover J, Hoffman DR, Castaneda YS et al. Three randomized controlled trials of early long-chain polyunsaturated Fatty Acid supplementation on means-end problem solving in 9-month-olds. Child Dev 2009;80:1376-84.
  6. Morale SE, Hoffman DR, Castaneda YS et al. Duration of long-chain polyunsaturated fatty acids availability in the diet and visual acuity. Early Hum Dev 2005;81:197-203.
  7. Du Toit G, Meyer R, Shah N et al. Identifying and managing cow's milk protein allergy. Arch Dis Child Educ Pract Ed 2010;95:134-44.
  8. Walker-Smith JA. Food sensitive enteropathies. Clin Gastroenterol 1986;15:55-69.
  9. Goulet O. Lipid requirements in infants with digestive diseases with references to short bowel syndrome. Eur J Med Res 1997;2:79-83.
  10. Jeppesen PB, Mortensen PB. Colonic digestion and absorption of energy from carbohydrates and medium-chain fat in small bowel failure. J Parenter Enteral Nutr 1999;23:S101-S105.
  11. Jirapinyo P, Young C, Srimaruta N et al. High-fat semielemental diet in the treatment of protracted diarrhea of infancy. Pediatrics 1990;86:902-8.
  12. Lifschitz CH, Carrazza F. Effect of formula carbohydrate concentration on tolerance and macronutrient absorption in infants with severe, chronic diarrhea. J Pediatr 1990;117:378-83.
  13. Vanderhoof J. Fat Malabsorption. In:  Nutrition for Special Needs in Infancy. Lifschitz F, editors. Marcel Dekker, New York and Basel; 1985, pp 159-73.
  14. Kaufman SS, Scrivner DJ, Murray ND et al. Influence of portagen and pregestimil on essential fatty acid status in infantile liver disease. Pediatrics 1992;89:151-4.