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This website is intended for healthcare professionals and contains information about Mead Johnson Nutrition special infant formulas.

Important Notice: Breast feeding provides the best nutrition for babies. Mead Johnson special formulas are intended for bottle-fed infants and are Food for Special Medical Purposes (FSMPs) and must be used under medical supervision.

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Please note that the Nutramigen LIPIL product range in Ireland is slightly different to the UK.

Information on the complete range of Nutramigen products available in the Republic of Ireland can be found on this page.

For the UK Nutramigen product range, click here

Republic of Ireland Product Range


For further information on Nutramigen LIPIL 1 & 2 please read below.

To learn more about the rest of the Nutramigen product range available in the Republic of Ireland please use the links below:

Nutramigen PURAMINO

Pregestimil LIPIL

Enfamil A.R

Enfamil O-Lac

Nutramigen LIPIL 1 and 2

First-line for cow’s milk allergy

Nutramigen LIPIL is the UK and Ireland’s leading hypoallergenic formula, supported by over 70 studies and over 70 years of experience in managing infants with cow’s milk allergy (CMA).

Expert guidelines

Guidelines recommend extensively hydrolysed formulas (eHFs) with proven clinical efficacy as the first-line choice for bottle/formula-fed infants with mild-to-moderate CMA1 as they provide symptom relief to 90% of infants with CMA2

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  • Nutramigen LIPIL 1 and 2 are eHFs indicated for the management of CMA.
  • Nutramigen LIPIL has staged formulas tailored to the needs of the developing infant
  • The most extensively hydrolysed formula,3 with the lowest allergenic potential4

Clinically proven efficacy


The hydrolysis process

Watch the video below to learn how the protein in Nutramigen LIPIL is broken down to make it hypoallergenic. Nutramigen LIPIL is the most extensively hydrolysed formula available.3

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  • Clinically proven for effective management of CMA symptoms, such as atopic eczema and other skin problems5-7
  • Effective for managing colic due to CMA within 48 hours8,9

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  • Suitable for use in diagnostic elimination diets2
  • Lactose free
  • Enriched with LIPIL containing 0.3% DHA of total fatty acids, which is proven to support normal cognitive and visual development1013

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The only eHF clinically proven to accelerate time to tolerance14

Oral tolerance means an infant can consume cow’s milk again without allergic reactions. The quicker the time to oral tolerance, the quicker the time to a life free from the burden of CMA.15

Nutramigen LIPIL is the only eHF clinically proven to accelerate time to tolerance. 54% of infants on Nutramigen LIPIL are tolerant to cow’s milk after 12 months’ intake.17

This has many benefits for the quality of life of the infant and their family, and for your budget. Visit our tolerance page to find out more.

Nutramigen LIPIL 2: First-class nutrition for older babies


CMA imposes a number of important nutritional challenges during weaning. Key among these are ensuring sufficient calcium intake on a dairy-free diet, and providing a varied and nutritionally adequate diet.

Learn more

  • Nutramigen LIPIL 2 is tailored to meet the needs of infants with CMA during weaning and beyond
  • Nutramigen LIPIL 2 is the only hypoallergenic formula to meet the calcium requirements of babies
  • Nutramigen LIPIL 2 provides more calcium in less volume, which can be beneficial if formula intake decreases during weaning.

Learn more


Show references
  1. Venter C et al. Diagnosis and management of non-IgE-mediated cow's milk allergy in infancy - a UK primary care practical guide. Clin Trans Allergy 2013;3:23.

  2. Vandenplas Y, Koletzko S, Isolauri E et al. Guidelines for the diagnosis and management of cow's milk protein allergy in infants. Arch Dis Child 2007;92:902-8.

  3. Du Toit G, Meyer R, Shah N et al. Identifying and managing cow's milk protein allergy. Arch Dis Child Educ Pract Ed 2010;95:134-44.

  4. Rosendal A, Barkholt V. Detection of potentially allergenic material in 12 hydrolyzed milk formulas. J Dairy Sci 2000;83:2200-10.

  5. Isolauri E, Sutas Y, Makinen-Kiljunen S et al. Efficacy and safety of hydrolyzed cow milk and amino acid-derived formulas in infants with cow milk allergy. J Pediatr 1995;127:550-7.

  6. Oldaeus G, Bradley CK, Bjorksten B, Kjellman NI. Allergenicity screening of "hypoallergenic" milk-based formulas. J Allergy Clin Immunol 1992;90:133-5.

  7. Rugo E, Wahn U. [In vivo studies of residual allergen activity of hydrolysate feeding]. Monatsschr Kinderheilkd 1992;140:472-5.

  8. Lothe L, Lindberg T, Jakobsson I. Cow's milk formula as a cause of infantile colic: a double-blind study. Pediatrics 1982;70:7-10.

  9. Lothe L, Lindberg T. Cow's milk whey protein elicits symptoms of infantile colic in colicky formula-fed infants: a double-blind crossover study. Pediatrics 1989;83:262-6.

  10. Birch EE, Carlson SE, Hoffman DR et al. The DIAMOND (DHA Intake And Measurement Of Neural Development) Study: a double-masked, randomized controlled clinical trial of the maturation of infant visual acuity as a function of the dietary level of docosahexaenoic acid. Am J Clin Nutr 2010;91:848-59.

  11. Drover J, Hoffman DR, Castaneda YS et al. Three randomized controlled trials of early long-chain polyunsaturated Fatty Acid supplementation on means-end problem solving in 9-month-olds. Child Dev 2009;80:1376-84.

  12. Morale SE, Hoffman DR, Castaneda YS et al. Duration of long-chain polyunsaturated fatty acids availability in the diet and visual acuity. Early Hum Dev 2005;81:197-203.

  13. Birch EE et al. Visual acuity and cognitive outcomes at 4 years of age in a double-blind, randomized trial of long-chain polyunsaturated fatty acid-supplemented infant formula. Early Hum Dev 2007;83:279-284.

  14. Canani R et al. Effect of Lactobacillus GG on tolerance acquisition in infants with cow’s milk allergy: A randomized trial. Jour All Clin Immunol 2012;129:580–582.

  15. Cummings AJ et al. The psychosocial impact of food allergy and food hypersensitivity in children, adolescents and their families: a review. Allergy 2010;65:933−945.

  16. Nutricia Ltd. Aptamil Pepti 2 datacard. www.aptamilprofessional.co.uk [Last accessed October 2012].

  17. Nutricia Ltd. Neocate LCP datacard. www.nutricia.co.uk/neocate/home [Last accessed October 2012].