Nutramigen LGG^® 1

An extensively hydrolysed hypoallergenic formula designed to meet the daily needs of infants with cow's milk allergy (CMA). It is nutritionally complete from 0–6 months and as part of a weaning diet from 6 months onwards.

From birth onwards

Prescribing Guide

Key features

Dual action ingredients:

Lactobacillus rhamnosus (LGG®) and the unique peptide size resolve gut dysbiosis and regulate the immune system.^1–4

Recommended by ESPGHAN and WAO/DRACMA for gastrointestinal symptoms^5,6

Fast symptom relief:

Nutramigen LGG® offers an average clinical efficacy of 99% in managing symptoms,*⁷ such as crying and infant colic within 48 hours^†8

Supports return to milk:

2x more infants with CMA returned to cow’s milk after 1 year vs. with any other CMA formula^‡§

Reduces future allergies:

57% fewer infants developed allergic manifestations over 3 years^‡¶

What makes Nutramigen LGG^® different?

LGG® works together with extensively hydrolysed casein protein to rebalance the immune response.^2,9,10

Nutramigen LGG® returned 2X more infants to milk over 12 months vs. any other CMA formula^‡§2and is the only formula clinically proven to reduce the risk of future allergic manifestations vs. whey-based eHF.^¶2

View the clinical summary

More information?

Download the product data card for more information on the indication, ingredients, nutritional composition, feeding guidelines and instructions for use.

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Glucose syrup, vegetable oils (palm olein, coconut, soya, high oleic sunflower), extensively hydrolysed casein (from milk), modified corn starch, calcium citrate, potassium phosphate, calcium phosphate, oil from Mortierella alpina, potassium chloride, magnesium phosphate, oil from the microalgae Schizochytrium sp., choline chloride, sodium chloride, L-cystine, inositol, ascorbic acid, L-tyrosine, L-tryptophan, taurine, ferrous sulphate, Lactobacillus rhamnosus (LGG®) bacteria culture (0.02%), L-carnitine, DL-alpha tocopheryl acetate, zinc sulphate, ascorbyl palmitate, nicotinamide, retinyl palmitate, calcium pantothenate, cupric sulphate, thiamin hydrochloride, riboflavin, pyridoxine hydrochloride, manganese sulphate, sodium iodide, folic acid, sodium molybdate, phytomenadione, chromic chloride, sodium selenite, D-biotin, cholecalciferol, cyanocobalamin.

Nutrients	Units	Per 100g powder	Per 100ml reconstituted
Energy	kJ (kcal)	2098 (501)	284 (68)
Fat of which:	g	25	3.4
Saturates	g	10	1.35
Linoleic acid	g	4	0.54
α-Linolenic acid	mg	350	47
Arachidonic acid	mg	145	19.5
Docosahexaenoic acid	mg	115	15.5
Carbohydrate of which:	g	55	7.4
Sugars	g	5.7	0.77
Protein	g	14	1.88
Salt	g	0.6	0.08

Vitamins
Vitamin A, RE	μg	450	61
Vitamin D	μg	12.5	1.68
Vitamin E, α-Tocopherol	mg	4.5	0.61
Vitamin K	μg	65	8.7
Vitamin C	mg	60	8.1
Thiamin	mg	0.4	0.054
Riboflavin	mg	0.45	0.061
Niacin	mg	5	0.67
Vitamin B6	mg	0.3	0.04
Folate, DFE	μg	135	18.2
Folic acid	μg	80	10.8
Vitamin B12	μg	1.5	0.2
Biotin	μg	15	2
Pantothenic acid	mg	2.5	0.34

Minerals
Sodium	mg (mmol)	240 (10.2)	32 (1.37)
Potassium	mg (mmol)	610 (15.6)	82 (2.1)
Chloride	mg (mmol)	480 (13.5)	65 (1.82)
Calcium	mg (mmol)	570 (14.1)	76 (1.9)
Phosphorus	mg (mmol)	390 (12.6)	52 (1.69)
Magnesium	mg (mmol)	38 (1.54)	5 (0.21)
Iron	mg	9	1.21
Zinc	mg	3.5	0.47
Copper	mg	0.38	0.05
Manganese	mg	0.125	0.017
Selenium	μg	17.5	2.4
Chromium	μg	11	1.48
Molybdenum	μg	28	3.8

Others
Iodine	μg	115	15.5
Choline	mg	165	22
Inositol	mg	85	11.4
L-Carnitine	mg	12.5	1.68
Taurine	mg	30	4
Osmolarity	mOsm/L	270

For guidance only. Use the chart below for the correct amounts of cooled boiled room temperature water and powder.

Age	Approx. weight kg	Bottles/24h	Water ml	+Scoops*
0 - 2 weeks	<3 - 3.5	6	90	3
2 - 4 weeks	3.5 - 4	5 - 6	120	4
1 - 2 months	4 - 5	5	150	5
2 - 4 months	5 - 6.5	4 - 5	180	6
4 - 6 months	>6.5 kg	4	210	7
6 - 12 months	-	2 - 3	210	7
> 1 year	-	2	210	7

*Only use the scoop in the can to measure powder. 1 level scoop (4.5 g) to each 30 ml of water. Do not press powder into scoop and level off with the back of a clean and dry knife.

1.Wash hands and sterilize all utensils according to manufacturers' instructions.

2.Boil fresh water. Cool down to room temperature. Do not use softened water. Pour the desired amount of water into a clean bottle.

3.Add the required number of level scoops of powder (see feeding guidelines). Store dry scoop in the can.

4.Close bottle, roll and shake well until powder dissolves completely (approx. 1 minute). Check the temperature on the inside of your wrist.

5.Once prepared, the formula can spoil quickly. Feed immediately after preparation or cover and store in a refrigerator at 2-4°C for no longer than 24 hours. Do not freeze prepared formula and do not use if unrefrigerated for more than a total of 2 hours. Use the formula that has been in contact with your baby's mouth within 1 hour and do not refrigerate. Throw away prepared formula left in the bottle and clean utensils.

WARNING: We advise you carefully follow the instructions for preparation and use. Proper hygiene, preparation, dilution, use and storage are important when preparing formula. Do not use a microwave to warm the formula. Powdered formulas intended for infants are not sterile and should not be fed to premature infants or infants who are immunocompromised unless directed and supervised by a doctor.

IMPORTANT NOTICE:

Breastfeeding is best for babies and the nutritional benefits of breastfeeding should be carefully considered before bottle-feeding is initiated. The decision to discontinue breastfeeding may be difficult to reverse and the introduction of partial bottle-feeding may reduce breast milk supply. However, we recognise that breastfeeding may not be an option for every mother. Where a formula for special medical purposes is required, parents should only use this after consulting a healthcare professional. Preparation should follow label instructions; failure to do so may be harmful to the health of the child.

Guest JF, Fuller GW. J Comp Eff Res. 2019;8:449-459.
Nocerino R et al. J Pediatr. 2021;232:183–191.
Gao J et al. Front Microbiol. 2019;10:477.
Isolauri E et al. Gastroenterology. 1993;105:1643–150.
Koletzko S et al. JPGN. 2012;55:221-229.
Bognanni A et al. World Allergy Organ J. 2024;17:100888.
Dupont C et al. Br J Nutr. 2011;107:325-338.
Lothe L et al. Pediatrics. 1989;83:262–266.
Baldassarre ME et al. J Pediatr. 2010;156:397–401.
Canani RB et al. J Pediatr. 2013;163:777.e1.

*Calculated using data on allergic reactions after oral food challenge with an extensively hydrolysed formula from Table 3 of Dupont C et al. As judged by the Committee on Nutrition of the French Society of Paediatrics. Studied before the addition of LGG®.7 †In infants with CMPA-related colic. Study conducted before the addition of LGG®.8 ‡Over a 12-month period compared with other formulas indicated for CMA (eHF-WHEY, HRF, SF and AAF). Study was conducted in 2014 prior to the launch of Aptamil Pepti Syneo® and Neocate Syneo®.2 §41% of infants achieved immune tolerance at 12 months with Nutramigen LGG® vs. 19% with eHF-WHEY.^2 ¶Allergic manifestations include eczema, urticaria, asthma and rhinoconjunctivitis.²

Abbreviations

AAF, amino acid formula; CMA, cow's milk allergy; eHF, extensively hydrolysed formula; ESPGHAN, European Society for Paediatric Gastroenterology Hepatology and Nutrition; HRF, hydrolysed rice formula; SF, soy formula; WAO DRACMA, World Allergy Organization Diagnosis and Rationale for Action against Cow’s Milk Allergy.

RKT-M-75726 October 2025

Nutramigen LGG® 1