Nutramigen LGG® 2

An extensively hydrolysed hypoallergenic formula designed to meet the daily needs of infants with cow’s milk allergy (CMA), as part of a weaning diet from 6 months onwards.

6+ months

Prescribing Guide

Key features

Dual action ingredients:

Lactobacillus rhamnosus (LGG®) and the unique peptide size resolve gut dysbiosis and regulate the immune system.^1–4

Recommended by ESPGHAN and WAO/DRACMA for gastrointestinal symptoms^5,6

Proven taste acceptance:

Specifically developed taste profile helps acceptance in infants from 6 months onwards.⁷

Supports return to milk:

2x more infants with CMA returned to cow’s milk after 1 year vs. with any other CMA formula^†‡2

Reduces future allergies:

57% fewer infants developed an allergic manifestation over 3 years^*‡2

What sets Nutramigen LGG^® apart?

LGG^® works together with extensively hydrolysed casein protein to rebalance the immune response^2,8,9 and returned 2X more infants to milk over 12 months vs. any other CMA formula.*^†2 Nutramigen LGG^®is the only formula clinically proven to reduce the risk of future allergic manifestations vs. whey-based EHF^‡2

View the clinical summary

More information?

Download the product data card for more information on the indication, ingredients, nutritional composition, feeding guidelines and instructions for use.

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Glucose syrup, vegetable oils (palm olein, coconut, soy, high oleic sunflower, extensively hydrolysed casein from milk, fructose, modified corn starch, calcium citrate, potassium citrate, calcium phosphate, magnesium phosphate, potassium chloride, oil from mortierella alpina, oil from the microalgae schizochytrium sp., L-Cystine, choline chloride, sodium citrate, L-Tyrosine, inositol, ascorbic acid, L-Tryptophan, ferrous sulfate, taurine, Lactobacillus rhamnosus (LGG®)bacteria culture 0.02%, zinc sulfate, L-Carnitine, nicotinamide, DL-alpha tocopheryl acetate, ascorbyl palmitate, calcium pantothenate, retinyl palmitate, cupric sulfate, pyridoxine hydrochloride, riboflavin, thiamine hydrochloride, manganese sulfate, sodium iodide, folic acid, chromic chloride, phytomenadione, sodium molybdate, sodium selenite, D-Biotin, cholecalciferol, cyanocobalamin.

Nutrients	Units	Per 100g powder	Per 100ml reconstituted
Energy	kJ (kcal)	2107 (503)	285 (68)
Fat of which:	g	25	3.4
Saturates	g	10.5	1.41
Linoleic acid	g	4	0.54
α-Linolenic acid	mg	350	47
Arachidonic acid	mg	145	19.5
Docosahexaenoic acid	mg	115	15.5
Carbohydrate of which:	g	57	7.7
Sugars	g	26	3.5
Protein	g	12.5	1.68
Salt	g	0.44	0.06

Vitamins
Vitamin A, RE	μg	480	65
Vitamin D	μg	12.5	1.68
Vitamin E	mg	5	0.67
Vitamin K	μg	40	5.4
Vitamin C	mg	55	7.4
Thiamin	mg	0.48	0.065
Riboflavin	mg	0.63	0.084
Niacin	mg	7.7	1.04
Vitamin B6	mg	0.65	0.087
Folate, DFE	μg	100	13.5
Folic acid	μg	60	8.1
Vitamin B12	μg	1.05	0.141
Biotin	μg	10.5	1.41
Pantothenic acid	mg	3.8	0.5

Minerals
Sodium	mg (mmol)	175 (7.6)	24 (1.02)
Potassium	mg (mmol)	700 (17.9)	94 (2.4)
Chloride	mg (mmol)	350 (9.9)	47 (1.33)
Calcium	mg (mmol)	600 (15.0)	81 (2.0)
Phosphorus	mg (mmol)	350 (11.3)	47 (1.52)
Magnesium	mg (mmol)	60 (2.5)	8.1 (0.33)
Iron	mg	8	1.08
Zinc	mg	5.5	0.74
Copper	mg	0.38	0.05
Manganese	mg	0.15	0.02
Selenium	μg	17.5	2.4
Chromium	μg	15	2
Molybdenum	μg	15.5	2.1

Others
Iodine	μg	115	15.5
Choline	mg	120	16.1
Inositol	mg	85	11.4
L-Carnitine	mg	11	1.48
Taurine	mg	30	4
Osmolarity	mOsm/L	351

For guidance only. Use the chart below for the correct amounts of cooled boiled room temperature water and powder.

Age	Bottles/24h	Water ml	+Scoops*	Average ml of feeding
6 - 12 months	2 - 3	210	7	230
> 1 year	2	210	7	230

*Only use the scoop in the can to measure powder. 1 level scoop (4.5 g) to each 30 ml of water. Do not press powder into scoop and level off with the back of a clean and dry knife.

1.Wash hands and sterilize all utensils according to manufacturers' instructions.

2.Boil fresh water. Cool down to room temperature. Do not use softened water. Pour the desired amount of water into a clean bottle.

3.Add the required number of level scoops of powder (see feeding guidelines). Store dry scoop in the can.

4.Close bottle, roll and shake well until powder dissolves completely (approx. 1 minute). Check the temperature on the inside of your wrist.

5.Once prepared, the formula can spoil quickly. Feed immediately after preparation or cover and store in a refrigerator at 2-4°C for no longer than 24 hours. Do not freeze prepared formula and do not use if unrefrigerated for more than a total of 2 hours. Use the formula that has been in contact with your baby's mouth within 1 hour and do not refrigerate. Throw away prepared formula left in the bottle and clean utensils.

WARNING: We advise you carefully follow the instructions for preparation and use. Proper hygiene, preparation, dilution, use and storage are important when preparing formula. Do not use a microwave to warm the formula. Powdered formulas intended for infants are not sterile and should not be fed to premature infants or infants who are immunocompromised unless directed and supervised by a doctor.

IMPORTANT NOTICE:

Breastfeeding is best for babies and the nutritional benefits of breastfeeding should be carefully considered before bottle-feeding is initiated. The decision to discontinue breastfeeding may be difficult to reverse and the introduction of partial bottle-feeding may reduce breast milk supply. However, we recognise that breastfeeding may not be an option for every mother. Where a formula for special medical purposes is required, parents should only use this after consulting a healthcare professional. Preparation should follow label instructions; failure to do so may be harmful to the health of the child.

Guest JF, Fuller GW. J Comp Eff Res. 2019;8:449-459.
Nocerino R et al. J Pediatr. 2021;232:183–191.
Gao J et al. Front Microbiol. 2019;10:477.
Isolauri E et al. Gastroenterology. 1993;105:1643–150.
Koletzko S et al. JPGN. 2012;55:221-229.
Bognanni A et al. World Allergy Organ J. 2024;17:100888.
Reckitt Data on File. Parental Experiences in CMA. March 2023.
Baldassarre ME et al. J Pediatr. 2010;156:397–401.
Canani RB et al. J Pediatr. 2013;163:777.e1.

Abbreviations

AAF, amino acid formula; CMA, cow's milk allergy; eHF, extensively hydrolysed formula; ESPGHAN, European Society for Paediatric Gastroenterology Hepatology and Nutrition; HRF, hydrolysed rice formula; SF, soy formula; WAO DRACMA, World Allergy Organization Diagnosis and Rationale for Action against Cow’s Milk Allergy.

*Over a 12-month period compared with other formulas indicated for CMA (eHF-WHEY, HRF, SF and AAF). Study was conducted in 2014 prior to the launch of Aptamil Pepti Syneo® and Neocate Syneo®.2 †41% of infants achieved immune tolerance at 12 months with Nutramigen LGG® vs. 19% with eHF-WHEY.^2 ‡Allergic manifestations include eczema, urticaria, asthma and rhinoconjunctivitis.²

RKT-M-75726 October 2025