Nutramigen Puramino^®

An amino acid-based hypoallergenic formula suitable for infants from birth as the sole source of nutrition and as part of a weaning diet from 6 months onwards.

It is recommended for infants with severe cow's milk allergy (CMA), multiple food allergies or conditions where an amino acid-based formula (AAF) is recommended. It is also for infants with other conditions where an elemental diet is recommended, including eosinophilic esophagitis and faltering growth.

From birth onwards

Prescribing Guide

Key features

Fast symptom resolution:

Proven to be fast and effective in managing CMA symptoms^1,2*

Nutritionally complete:

Proven to support normal growth^1*† and can be used as a sole source of nutrition in infants up to 6 months of age or as part of a varied diet for older infants and young children

Specially formulated with MCT:

Contains 33%^‡ of medium chain triglycerides (MCTs)^§ to provide an easily available source of fat and energy in case of fat malabsorption^3,4

Halal and Kosher certified

Supporting the NHS and your practice

Did you know?

AAF prices have surged by 14% since 2022.^¶

We remain committed to providing you and your patients with a cost-effective, high-quality formula. Nutramigen Puramino^® is 10% cheaper than Neocate^®LCP and 11% cheaper than Alfamino^®.⁵

By choosing Puramino^®, the NHS could save between £4.5m and £8m annually.^||

More information?

Download the product data card for more information on the indication, ingredients, nutritional composition, feeding guidelines and instructions for use.

Download datacard

Glucose syrup, vegetable oils (high oleic sunflower, medium chain triglycerides from coconut/palm kernel (9.3%), soya), modified tapioca starch, potassium aspartate, L-leucine, L-lysine hydrochloride, calcium phosphate, L-proline, L-alanine, L-valine, L-isoleucine, monosodium glutamate, L-threonine, L-serine, L-tyrosine, L-aspartate, L-arginine, L-phenylalanine, magnesium phosphate, L-histidine, L-cystine, glycine, L-tryptophan, oil from Mortierella alpina, L-methionine, potassium chloride, oil from the microalgae Schizochytrium sp., calcium citrate, choline chloride, sodium citrate, inositol, ascorbic acid, ferrous sulphate, taurine, zinc sulphate, L-carnitine, DL-alpha tocopheryl acetate, nicotinamide, calcium pantothenate, retinyl palmitate, cupric sulphate, pyridoxine hydrochloride, thiamin hydrochloride, riboflavin, manganese sulphate, sodium iodide, chromic chloride, folic acid, phytomenadione, sodium selenite, sodium molybdate, D-biotin, cholecalciferol, cyanocobalamin.

Nutrients	Units	Per 100g powder	Per 100ml reconstituted
Energy	kJ (kcal)	2140 (510)	285 (68)
Fat of which:	g	28	3.7
Saturates	g	10.7	1.41
Linoleic acid	g	3.5	0.46
α-Linolenic acid	mg	370	49
Arachidonic acid	mg	148	19.5
Docosahexaenoic acid	mg	117	15.5
Carbohydrate of which:	g	52	6.9
Sugars	g	4.2	0.55
Protein	g	14.3	1.88
Salt	g	0.42	0.06

Vitamins
Vitamin A, RE	μg	430	57
Vitamin D	μg	12.25	1.63
Vitamin E	mg	4.6	0.61
Vitamin K	μg	46	6.1
Vitamin C	mg	48	6.4
Thiamin	mg	0.31	0.04
Riboflavin	mg	0.41	0.054
Niacin	mg	4.7	0.63
Vitamin B6	mg	0.38	0.05
Folate, DFE	μg	87	11.4
Folic acid	μg	52	6.9
Vitamin B12	μg	0.92	0.121
Biotin	μg	12.2	1.62
Pantothenic acid	mg	2.9	0.38

Minerals
Sodium	mg (mmol)	168 (7.3)	22 (0.97)
Potassium	mg (mmol)	730 (18.7)	96 (2.5)
Chloride	mg (mmol)	450 (12.8)	60 (1.69)
Calcium	mg (mmol)	580 (14.4)	76 (1.9)
Phosphorus	mg (mmol)	330 (10.7)	44 (1.41)
Magnesium	mg (mmol)	61 (2.5)	8.1 (0.33)
Iron	mg	7.7	1.01
Zinc	mg	4.6	0.61
Copper	mg	0.38	0.05
Manganese	mg	0.087	0.011
Selenium	μg	18.4	2.4
Chromium	μg	26	3.4
Molybdenum	μg	15.8	2.1

Others
Iodine	μg	102	13.5
Choline	mg	163	22
Inositol	mg	87	11.4
L-Carnitine	mg	10.2	1.35
Taurine	mg	31	4
Osmolarity	mOsm/L	314

The recommended volume of Nutramigen Puramino® must be determined by a healthcare professional, and is dependent on age, body weight, type of medical condition and other foods consumed. Use table below as a guidance:

Age	Approx. weight		Bottles/24h	Water		+Scoops*	Average amount of feeding (ml)
Age	kg	lbs	Bottles/24h	ml	fl.oz	+Scoops*	Average amount of feeding (ml)
0 - 2 weeks	< 3 - 3.5	6 ½ - 7 ½	6 – 7	90	3	3	100
2 - 4 weeks	3.5 – 4	7 ½ - 8 ½	5 – 6	120	4	4	130
1 - 2 months	4 – 5	8 ½ - 11	5	150	5	5	170
2 - 4 months	5 – 6.5	11 – 14	4 - 5	180	6	6	200
4 - 6 months	6.5 – 7.5	14 – 16 ½	4	210	7	7	230
6 - 12 months	7.5 – 9.5	16 ½ - 20 ½	2 – 3	240	8	8	260
> 1 year	> 9.5	20 ½	2 – 3	240	8	8	260

*Only use the scoop in the can to measure powder. 1 level scoop (4.5 g) to each 30 ml of water. Do not press powder into scoop and level off with the back of a clean and dry knife.

1.Wash hands and sterilize all utensils according to manufacturers' instructions.

2.Boil fresh water. Cool down to room temperature. Do not use softened water. Pour the desired amount of water into a clean bottle.

3.Add the required number of level scoops of powder (see feeding guidelines). Store dry scoop in the can.

4.Close bottle, roll and shake well until powder dissolves completely (approx. 1 minute). Check the temperature on the inside of your wrist.

5.Once prepared, the formula can spoil quickly. Feed immediately after preparation or cover and store in a refrigerator at 2-4°C for no longer than 24 hours. Do not freeze prepared formula and do not use if unrefrigerated for more than a total of 2 hours. Use the formula that has been in contact with your baby's mouth within 1 hour and do not refrigerate. Throw away prepared formula left in the bottle and clean utensils.

WARNING: We advise you carefully follow the instructions for preparation and use. Proper hygiene, preparation, dilution, use and storage are important when preparing formula. Do not use a microwave to warm the formula. Powdered formulas intended for infants are not sterile and should not be fed to premature infants or infants who are immunocompromised unless directed and supervised by a doctor.

IMPORTANT NOTICE:

Breastfeeding is best for babies and the nutritional benefits of breastfeeding should be carefully considered before bottle-feeding is initiated. The decision to discontinue breastfeeding may be difficult to reverse and the introduction of partial bottle-feeding may reduce breast milk supply. However, we recognise that breastfeeding may not be an option for every mother. Where a formula for special medical purposes is required, parents should only use this after consulting a healthcare professional. Preparation should follow label instructions; failure to do so may be harmful to the health of the baby.

Burks W et al. J Pediatr. 2008;153:266–271.
Vanderhoof J et al. J Pediatr Gastroenterol Nutr. 2016;63:531–533.
Bach AC, Babayan VK. Am J Clin Nutr. 1982;36:950–962.
Akoh CC. Handbook of functional lipids. CRC Press 2005.
MIMS (Nutramigen, Neocate, SMA). July 2025.

Abbreviations

AAF, amino acid formula; CMA, cow's milk allergy; MCT, medium chain triglyceride.

*Studied before the addition of MCTs. †Studied in healthy full-term infants. ‡% of total fat. §MCTs are a fat source derived from palm kernel and coconut oils. They are digested and absorbed faster and more easily than long chain fatty acids. The MCT in Nutramigen Puramino® will therefore improve the availability of nutrients and energy for infants with severe cow's milk protein allergy in conjunction with poor digestion of standard fats, such as those with severe enteropathies that result in maldigestion and malabsorption. ¶Based on AAF costs per tin provided by manufacturers nationally in the UK from 2022 to 2024. ||Assuming Puramino® is selected as the primary choice nationally over other brands (including Neocate® Junior), this cost reflects the savings made per year.

RKT-M-75726 October 2025